Colon Cancer Screening Options in Northern Virginia: Colonoscopy, Stool, and Blood Tests

Colon Cancer Screening Options in Northern Virginia: Colonoscopy, Stool, and Blood Tests

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Choosing colon cancer screening in Northern Virginia does not have to be confusing, even though there are now several tests to consider. The right test is, in large part, the one that fits your situation and that you will actually complete. This guide compares the main options, colonoscopy, stool-based tests, and blood-based tests, so you can have an informed conversation with your gastroenterologist about which path makes sense for you.

This article is general education, not medical advice. Your screening plan should be set with a physician who knows your personal and family history.

Why colon cancer screening matters

Most colorectal cancers begin as small growths called polyps that develop slowly over many years. Screening looks for those changes early, often before any symptoms appear, when there is the most time to act. That is the core idea behind colon cancer screening in Northern Virginia and everywhere else: catch problems early, when they are easiest to address. Some screening tests look for cancer that is already present, while others, like colonoscopy, can find and remove polyps before they ever turn into cancer. Understanding that difference helps explain why the tests are not all interchangeable.

When colon cancer screening should start

For adults at average risk, the American Cancer Society updated its guidance in 2026 and continues to recommend starting at age 45. The U.S. Preventive Services Task Force also recommends colorectal cancer screening for average-risk adults from age 45 to 75, with the decision to continue between ages 76 and 85 made individually with a physician. Our guide to colon cancer screening after 75 explains how that decision is made. You can review the current recommendations directly from the American Cancer Society.

Some people should begin earlier or screen more often, including those with a family history of colorectal cancer or polyps, inflammatory bowel disease, or certain inherited conditions. If that describes you, a gastroenterologist can recommend a starting age and interval based on your history rather than the average-risk default.

Colonoscopy: the option that detects and removes polyps

Colonoscopy is widely considered the gold standard for colon cancer screening in Northern Virginia because it does two jobs in one visit. A gastroenterologist uses a thin, flexible camera to examine the lining of the colon and rectum, and many polyps that are found can be removed during the same exam. That ability to both detect and remove growths in a single step is what sets colonoscopy apart from the other tests.

The trade-offs are practical ones. Colonoscopy requires a bowel preparation the day before, sedation during the exam, and a ride home afterward, and for average-risk adults with a normal result it is generally repeated every 10 years. We cover the preparation and the exam itself in our companion guide to colonoscopy in Northern Virginia and what to expect, so we will not repeat those mechanics here.

Stool-based tests: FIT and multitarget stool tests

Stool-based tests are done at home and look for signs of cancer in a stool sample, which makes them convenient and avoids both the bowel prep and the sedation that colonoscopy requires. The fecal immunochemical test, or FIT, checks for hidden blood and is typically repeated every year. Multitarget stool tests look for blood along with altered DNA shed by abnormal cells and are generally repeated every few years. Both are recognized, guideline-backed choices for average-risk adults.

The main limitation is that stool-based tests detect signs of a problem but cannot remove anything. They also need to be repeated on schedule to stay effective, and they can occasionally miss findings or flag something that turns out to be benign. Importantly, a stool test is only a complete screening strategy when you follow through on the repeat testing and on any recommended next steps.

Blood-based tests: recommended but not preferred

Blood-based screening tests are a newer option that look for signals of colorectal cancer in a blood sample drawn during a regular visit. For people who would otherwise skip screening altogether, having an additional, low-effort choice is meaningful. Guideline groups describe these tests as recommended but not preferred, meaning they are a reasonable option when a colonoscopy or a stool-based test will not be done.

The reason they are not preferred is that current blood tests are generally better at detecting existing cancer than at finding the early polyps that other tests catch, and like stool and blood tests in general, they cannot remove anything. They are most useful as a way to screen someone who would not otherwise be screened, not as a replacement for colonoscopy when colonoscopy is an option.

Comparing the options: how to weigh pros and cons

Each test trades convenience against thoroughness in a different way. Colonoscopy is the most comprehensive because it both finds and removes polyps, but it asks the most of you in preparation and time. Stool-based tests are easy to do at home and need no prep or sedation, but they must be repeated regularly and cannot treat anything. Blood-based tests are the simplest to complete, yet they are the least preferred and are aimed mainly at people who would otherwise have no screening at all.

There is no single answer that fits everyone. The most useful comparison is a personal one, and a gastroenterologist can help you weigh your risk level, your preferences, and how likely you are to stay on schedule with a given test.

The key rule: a positive test needs a follow-up colonoscopy

One point ties all of these options together. If a stool-based or blood-based test comes back positive, the recommended next step is a colonoscopy to find out what caused the result. A positive non-colonoscopy test is not a diagnosis; it is a signal that a closer look is needed. This is the most important thing to understand before choosing a test, because the screening is only finished when an abnormal result is followed up properly. If you would like to understand what colonoscopy can find, our guide to colon polyps and colorectal cancer in Northern Virginia explains how polyps relate to cancer risk.

Colon cancer screening in Northern Virginia with GC of NoVA

Gastroenterology Center of Northern Virginia provides colon cancer screening and colonoscopy for patients across Arlington, Annandale, and the surrounding Northern Virginia communities. Our physicians perform procedures at VHC Health, Inova Fairfax Hospital, and the Woodburn Endoscopy Center, and we see patients at two offices: Arlington, next to VHC Health, and Annandale, in the Woodburn Medical complex. If you are due to start screening or are weighing which test fits you, we are glad to help you understand the options.

To talk through your choices or schedule a screening consultation, contact our Arlington office at (703) 522-7476 or our Annandale office at (703) 560-6106, or learn more at gcofnova.com.

Frequently asked questions about colon cancer screening in Northern Virginia

At what age should colon cancer screening start?

For average-risk adults, the American Cancer Society and the U.S. Preventive Services Task Force recommend starting at age 45. People with a family history or other risk factors may need to begin earlier, which a gastroenterologist can help determine.

Which colon cancer screening test is the most thorough?

Colonoscopy is considered the gold standard because it is the only test that can both find polyps and remove many of them in the same exam. Stool-based and blood-based tests can detect signs of a problem but cannot remove anything.

What happens if a stool or blood test is positive?

A positive stool-based or blood-based test is a signal, not a diagnosis. The recommended next step is a colonoscopy to look closely and find out what caused the result, which is why follow-up is an essential part of these screening options.

How do I choose a screening test in Arlington or Annandale?

The right choice depends on your risk level, your preferences, and how likely you are to stay on schedule. A gastroenterologist at our Arlington or Annandale office can review your history and help you decide which option fits your situation.

This article is for general education and is not medical advice. Talk with a qualified gastroenterologist about your symptoms, diagnosis, and treatment options.

About us



We would like to welcome you to the Gastroenterology Center of Northern Virginia, Ltd. We appreciate the opportunity to participate in your care. It is our sincere desire to provide you with the highest quality and most comprehensive services in the diagnosis, treatment and management of various digestive conditions.

Arlington Address


1715 N George Mason Dr, Suite 403, Arlington, VA 22205
(adjacent to VHC Health, Zone C,
Parking C )
Phone: (703) 522-7476
Fax: (703) 528-4209
Office hours:
Monday – Thursday 8:30 am – 5:00 pm
Friday 8:30 am – 4:30 pm

Annandale Address


3299 Woodburn Road, Suite 220 Annandale, VA 22003
(second building in the Woodburn Medical complex)
Phone: (703) 560-6106
Fax: (703) 204-1968
Office hours:
Monday - Thursday 8:30 am – 5:00 pm
Friday 8:30 am – 4:30 pm
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